Recombinant Rat EphA3 Protein (Fc tag)
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
Synonym(s) : EPHA3
Species(s) : Rat
Protein Expression Host : Human Cells
Protein Construction : A DNA sequence encoding the rat EPHA3 (EDL75897.1) (Met1-His541) was expressed with the Fc region of human IgG1 at the C-terminus.
Predicted N-terminal amino acid : Glu 21
Molecular weight/mass : The recombinant rat EPHA3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 762 amino acids and has a predicted molecular mass of 85.8 kDa. The apparent molecular mass of the protein is approximately 103 kDa in SDS-PAGE under reducing conditions.
Protein Construction : A DNA sequence encoding the rat EPHA3 (EDL75897.1) (Met1-His541) was expressed with the Fc region of human IgG1 at the C-terminus.
Formulation : Lyophilized from sterile PBS, pH 7.4
Purity : > 95 % as determined by SDS-PAGE
Endotoxin level : < 1.0 EU per μg of the protein as determined by the LAL method
Stability : Samples are stable for up to twelve months from date of receipt at -70°C
Shipping conditions : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Reconstitution : Please refer to the printed manual for detailed information.
Additional information
Format | 200 ug, 500 ug |
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Species | Rat |
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