RIP3 Antibody
Background information :
Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
Alternate names: Receptor interacting protein 3, RIP 3, RIP like protein kinase 3, RIP3, RIPK3
Validated applications : ELISA | WB | IHC | IP
Suggested dilutions : WB: 1:200-1:1000, IP: 1:200-1:1000, IHC: 1:100-1:400
Calculated MW : 57 kDa
Conjugation : none
Clonality : Polyclonal
Isotype : IgG
Reactivity : Human | Mouse
Immunogen : receptor-interacting serine-threonine kinase 3
Purification method : Immunogen affinity purified
Purity : > 95% as determined by SDS-PAGE
Supplied as : liquid
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 24 months (Avoid repeated freeze / thaw cycles)
Swissprot ID : O14730
Gene ID :
Additional information
Format | 100 ug |
---|---|
Validated Applications | IP, WB, IHC, ELISA |
Host | Rabbit |
Reactivity | Human, Mouse |
Antibody Name | RIP3 Antibody |
Clonality | Polyclonal |
Supplier | |
Conjugation | None |
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