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RIP3 Antibody – FNab07312

  • Clonality : Rabbit Polyclonal
  • Applications : ELISA | WB | IHC | IP
  • Reactivity : Human | Mouse

$585.00 CAD

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RIP3 Antibody


Background information :

Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.


Alternate names: Receptor interacting protein 3, RIP 3, RIP like protein kinase 3, RIP3, RIPK3


Validated applications : ELISA | WB | IHC | IP


Suggested dilutions : WB: 1:200-1:1000, IP: 1:200-1:1000, IHC: 1:100-1:400


Calculated MW : 57 kDa


Conjugation : none


Clonality : Polyclonal


Isotype : IgG


Reactivity : Human | Mouse


Immunogen : receptor-interacting serine-threonine kinase 3


Purification method : Immunogen affinity purified


Purity : > 95% as determined by SDS-PAGE


Supplied as : liquid


Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 24 months (Avoid repeated freeze / thaw cycles)


Swissprot ID : O14730


Gene ID :


Manual & Datasheet


Additional information

Format

100 ug

Validated Applications

IP, WB, IHC, ELISA

Host

Rabbit

Reactivity

Human, Mouse

Antibody Name

RIP3 Antibody

Clonality

Polyclonal

Supplier

Conjugation

None

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