Encor Chicken Polyclonal to Pin-1
Pin-1 is a the peptidylprolyl cis/trans isomerase enzyme which is responsible, as its name suggests, for flipping the proline ring from the cis to the trans conformation. This enzyme is heavily upregulated in tumor cells, so that antibodies to this protein can be used as tumor markers. Pin-1 protein is concentrated in the nucleus in small punctate structures and is particularly obvious in tumor cells.
The HGNC name for this protein is Pin-1.
HGNC name(s) : –
Host : Chicken
Clonality : Polyclonal
ID : EnCor Biotechnology Pin1 Pin1
Reactivity : Human | Horse | Cow | Pig | Chicken | Rat | Mouse
Isotype : IgY
Conjugation : none
Immunogen : Yeast nuclear preparations
Mass of detected protein : 21 kDa
Uniprot ID :
KGNC name : –
Purification : Concentrated IgY preparation
Storage : Shipped on ice. Store at 4°C. For long term storage, leave frozen at -20°C. Avoid freeze / thaw cycles.
Validated applications : WB | IF/ICC | IHC
Suggested Dilutions:
WB: 1:10 000. IF/ICC and IHC: 1:500-1:1 000. ABC: 1:5 000.
References :
1. Lu KP, Hanes SD and Hunter T. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature 380 544-547, (1996).
Additional information
Format | 50 ul, 100 ul, 500 ul |
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Supplier | |
Host | Chicken |
Clonality | Polyclonal |
Conjugation | None |
Isotype | IgY |
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