Mouse CD19 / Leu-12 Protein (His tag) – PKSM040641

Recombinant Mouse CD19 / Leu-12 Protein (His tag)

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell coreceptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.

Synonym(s) : AW495831

Species(s) : Mouse

Protein Expression Host : Human Cells

Protein Construction : A DNA sequence encoding the extracellular domain of mouse CD19 (NP_663578.1) (Met 1-Gly 287) was expressed, with a polyhistidine tag at the C-terminus.

Predicted N-terminal amino acid : Gly 17

Molecular weight/mass : The recombinant mouse CD19 consists of 282 amino acids and has a predicted molecular mass of 31 kDa.

Protein Construction : A DNA sequence encoding the extracellular domain of mouse CD19 (NP_663578.1) (Met 1-Gly 287) was expressed, with a polyhistidine tag at the C-terminus.

Formulation : Lyophilized from sterile PBS, pH 7.4

Purity : > 90 % as determined by SDS-PAGE

Endotoxin level : < 1.0 EU per μg of the protein as determined by the LAL method

Stability : Samples are stable for up to twelve months from date of receipt at -70°C

Shipping conditions : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Reconstitution : Please refer to the printed manual for detailed information.

Manual & Datasheet