Anti-Histone H3 K27M Rabbit Monoclonal Antibody [RM192] – 31-1175-00

Histone H3 K27M Rabbit Monoclonal Antibody

Rabbit monoclonal to Histone H3 K27M

Histone H3 K27M Mutant antibody

Format : 100 ul

Concentration : 1 mg/mL

Reactivity : All Species. RM192 reacts to the Histone H3 K27M mutant. No cross reactivity with wild type Histone H3.

Clonality : Monoclonal

Clone name : RM192

Host species : Rabbit

Isotype : Rabbit IgG

Epitope : Mutant K27M in Histone H3

Uniprot ID : P84243

Gene ID : 8350

Purification method : Protein A affinity purified from an animal origin-free culture supernatant

Supplied in : 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Storage : -20.0°C

Immunogen : A peptide corresponding to Histone H3 K27M mutant

Validated applications : WB, ELISA, IHC, IF/ICC, ChIP

Suggested dilutions :

• WB: 0.01 (1:10 000) – 1 ug/ml (1:1000)
• ELISA: 0.5 (1:2000) – 2 ug/ml (1:500)
• IHC, ICC: 0.005 (1:20 000) – 0.1 ug/ml (1:1000)

Anti-Histone H3 K27M Rabbit Monoclonal Antibody Data Sheet RM192

Reference(s)

Pathania M et al. H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas Cancer Cell (2017) 10.1016/j.ccell.2017.09.014. IHC-P; Human. Read more (PubMed: 29107533)