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ABI1 Polyclonal Antibody – E-AB-15453

  • Clonality : Rabbit Polyclonal
  • Applications : WB | IHC | ELISA
  • Reactivity : Human | Mouse | Rat

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ABI1 Polyclonal Antibody


Background information : This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t (10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14


Research area(s) : Cancer | Cell biology


Alternate names: E3B1, ABI-1, ABLBP4, NAP1BP, SSH3BP, SSH3BP1


Validated applications : WB | IHC | ELISA


Suggested dilutions : WB 1:500-1:2000, IHC 1:50-1:200


Calculated MW : 55 kDa


Observed MW (if applicable)  :


Available sizes : 20 ul, 60 ul, 120 ul, 200 ul


Conjugation : none


Clonality : Polyclonal


Isotype : IgG


Clone number :


Reactivity : Human | Mouse | Rat


Immunogen : Synthetic peptide of human ABI1


Purification method : Affinity purification


Supplied in : PBS with 0.05% sodium azide,50% glycerol,pH 7.3


Concentration : 0.6 mg/mL


Storage : Store at-20 °C. Avoid freeze / thaw cycles.


Swissprot ID : Q8IZP0


Gene ID / Accession : / NP_005461


Other informations :

Link to Elabscience product page


Previous Catalog Number: ESAP15757


Manual & Datasheet


Additional information

Format

20 ul, 60 ul, 120 ul, 200 ul

Santa Cruz #

sc-20323, sc-30038

Product Name

ABI1 Polyclonal Antibody

Clonality

Polyclonal

Validated Applications

WB, IHC, ELISA

Reactivity

Human, Mouse, Rat

Research Area(s)

,

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